Cutting-edge Research by the Best and Brightest
Damon Runyon cancer researchers work in technologically advanced labs and leading hospitals across the country.Select a highlighted state to learn more about the scientists
and projects that Damon Runyon is currently funding.
Scientists by State
Boston Children's Hospital
Julia Su Zhou Li, PhD
“Uncovering the link between repetitive DNA, genomic instability, and tumor viruses”
Brigham and Women's Hospital
Jordan B. Jastrab, MD, PhD
"Molecular mechanisms of inflammasome activation by intraphagosomal bacteria"
with Jonathan C. Kagan, PhD
Vignesh Shanmugam, MD
"Uncovering microenvironmental dependencies in follicular lymphoma"
with Todd R. Golub, MD
Dana-Farber Cancer Institute
April A. Apfelbaum, PhD
"Investigation of receptor tyrosine kinase-independent mechanisms of FGFR1-mediated oncogenesis in pediatric gliomas"
with Pratiti Bandopadhayay, MBBS, PhD, and Keith L. Ligon, MD, PhD
Sylvan C. Baca, MD, PhD
"Epigenetic drivers of resistance to novel therapies for bladder and kidney cancer"
with Toni K. Choueiri, MD
Kheewoong Baek, PhD
"Expansion of the glueable and degradable targets of IMiD-CRBN"
with Eric S. Fischer, PhD
Wallace A. Bourgeois, MD
"Characterizing mechanisms of resistance to Menin inhibitors in KMT2A-rearranged and NPM1-mutant AML"
with Scott A. Armstrong, MD, PhD
Anders B. Dohlman, PhD
"Identifying the genomic basis for Fusobacterium nucleatum’s colonization of colorectal cancers"
with Matthew L. Meyerson, MD, PhD
Megan L. Insco, MD, PhD
"Targeting cancer-associated aberrant RNA to treat metastatic melanoma"
with F. Stephen Hodi, MD
(Peter) Geon Kim, MD
"Elucidating the mechanisms of inflammation in clonal hematopoiesis"
with Benjamin L. Ebert, MD, PhD
Costanza Lo Cascio, PhD
"Investigating the neuronal regulation of radioresistance in diffuse midline gliomas"
with Mariella G. Filbin, MD, PhD
James J. Morrow, MD, PhD
"Application of single-cell approaches to investigate the developmental origin and early transformation steps of osteosarcoma"
with Bradley E. Bernstein, MD, PhD
Matthew G. Oser, MD, PhD
"Dissecting and therapeutically exploiting synthetic lethality between NOTCH and TRIM28 to drive anti-tumor immunity in SCLC"
with William G. Kaelin, Jr., MD
Erin M. Parry, MD, PhD
"Defining follicular lymphoma transformation: molecular basis, detection and therapeutic vulnerabilities"
with Margaret A. Shipp, MD
Ahmed Roman, PhD
"Signal bottleneck theory for dissecting gene interactions in pancreatic cancer"
with Eliezer M. Van Allen, MD, and Andrew J. Aguirre, MD, PhD
Mounica Vallurupalli, MD
"Defining the mechanistic implications of SF3B1 mutations in MDS"
with Todd R. Golub, MD
Srinivas R. Viswanathan, MD, PhD
"X marks the spot: exploring how X-chromosome alterations drive sex differences in cancer"
David M. Walter, PhD
"Identifying the selective mechanism behind U2AF1 mutations in lung adenocarcinoma"
with Matthew L. Meyerson, MD, PhD
Lachelle D. Weeks, MD, PhD
"Predicting leukemia risk from peripheral blood smears"
with Benjamin L. Ebert, MD, PhD
Nina Weichert-Leahey, MD
"Elucidating the role of KAT6A and KAT6B in the epigenetic reprogramming of neuroblastoma to enforce neuronal differentiation"
with A. Thomas Look, MD
Harvard Medical School
Erin E. Duffy, PhD
"Activity-dependent changes in RNA stability as a mechanism for synaptic plasticity"
Lucas Farnung, PhD
"Understanding the mechanistic basis of gene expression regulation by MLL complexes in cancers"
Brooke D. Huisman, PhD
"Elucidating the lineage relationships of thymic mimetic cells"
with Diane Mathis, PhD, and Christophe Benoist, MD, PhD
Manuel Osorio Valeriano, PhD
"Molecular and structural basis of gene expression regulation by the nucleosome remodeling and deacetylase (NuRD) complex in human cancer"
with Lucas Farnung, PhD, and Danesh Moazed, PhD
Harvard T.H. Chan School of Public Health
Madi Y. Cissé, PhD
"Integration on oncogenic signaling and nutrient sensing by mTOR in tumors"
with Brendan D. Manning, PhD
Harvard University
Alon Chappleboim, PhD
"Uncovering signaling mechanisms in somitogenesis through high-throughput genetic screens in robust human organoids"
with Sharad Ramanathan, PhD
Massachusetts General Hospital
Charles H. Adelmann, PhD
"Systematic exploration of the organellar and cellular requirements of pigmentation"
with David E. Fisher, MD, PhD
Albert E. Kim, MD
"Using liquid biopsy and MRI to non-invasively identify therapeutic targets for brain metastases"
with Elizabeth R. Gerstner, MD
Massachusetts Institute of Technology
Fangtao Chi, PhD
"Understanding how ketone body metabolites influence intestinal stemness, immune responses and tumorigenesis"
with Ömer H. Yilmaz, MD, PhD
Isabella Fraschilla, PhD
"Examining bacteria as a source of tumor antigens"
with Tyler E. Jacks, PhD
J. Scott P. McCain, PhD
"Estimating growth rates and fluxes using gene expression: Theory and applications"
with Gene-Wei Li, PhD
Senén D. Mendoza, PhD
"Discovery and characterization of bacterial immunity against RNA phages"
with Michael T. Laub, PhD
Expery O. Omollo, PhD
"Elucidating what determines the strength of bacterial transcription terminators"
with Gene-Wei Li, PhD
Ian J. Roney, PhD
"Discovery and characterization of bacteriophage effectors of bacterial immune systems"
with Michael T. Laub, PhD
The Broad Institute of MIT and Harvard
Chaiheon Lee, PhD
"Development of haptenizing chimeras for neoantigen generation"
with Amit Choudhary, PhD
Whitehead Institute for Biomedical Research
Jingchuan Luo, PhD
“Decoding the role of localized translation in normal physiology and cancer metastasis”
Ryan Y. Muller, PhD
"Elucidating PABPC1 sequence preferences and determining how these preferences shape gene regulation"
with David P. Bartel, PhD
