Dr. Perry is investigating how a key immune cell in the tumor microenvironment, the macrophage, contributes to cancer’s development and progression. His work focuses on triple-negative breast cancer, as it remains one of the deadliest cancers, especially to young women and Black women, with decades of treatment efforts failing to improve patient outcomes. Specifically, Dr. Perry aims to combine novel methods of manipulating and imaging the cellular metabolism to better understand how macrophages contribute nutrients to help cancer cells meet their nutrient demand and escape treatment. This work will not only provide a method for diagnostic biomarker identification but also establish a novel platform for developing individualized treatments. Importantly, his work has the potential of being broadly applicable to all difficult-to-treat metastatic adenocarcinomas.
Damon Runyon Researchers
Meet Our ScientistsJustin Perry, PhD
Project title: "Tumor-macrophage metabolic symbiosis as a driver of disease progression and therapeutic resistance"
Institution: Memorial Sloan Kettering Cancer Center
Award Program: Innovator
Cancer Type: Breast
Research Area: Metabolism