Damon Runyon Researchers

Meet Our Scientists
Fangyu Liu, PhD

Dr. Liu’s research focuses on discovering new drug candidates to treat pancreatic, colorectal, breast, and prostate cancers. Using advanced computational techniques to screen billions of chemical compounds, she aims to identify and develop highly specific molecules that target critical pathways in cancer cells while sparing healthy tissues. For example, she has uncovered compounds that modulate calcium-sensing receptors, which play a role in certain cancers, with reduced side effects compared to the current standard-of-care. She is now applying these insights to improve treatments that boost immune responses against tumors. Dr. Liu’s work not only strives to create new cancer therapies but also deepen our understanding of the complex interactions within tumors, paving the way for precision medicine tailored to individual patients.

 
Project title: "Targeting membrane enzymes for next-generation precision medicine against cancer"
Institution: University of Texas Southwestern Medical Center
Award Program: Dale Frey Scientist
Cancer Type: Pancreatic, All Cancers
Research Area: Chemical Biology