Dr. Li [The Mark Foundation for Cancer Research Fellow] studies signaling events regulating the competition between cells carrying cancer-causing mutations and normal cells during cancer initiation. Previous studies have shown that intercellular signaling between mutant and normal cells could regulate the proliferation of these cells and shape the outcome of cancer initiation. Dr. Li is adapting novel tools to identify what molecular cues are mediating this crosstalk and how they contribute to cancer growth in mouse skin. Understanding these events may guide the development of cancer prevention strategies that restrict the early expansion of mutant cell lines in skin and other tissues. Dr. Li received her PhD from Duke University and her BS from Tsinghua University.
Damon Runyon Researchers
Meet Our ScientistsSiqi Li, PhD
Project title: "Deciphering clonal competition between oncogenic mutant and normal cells and its effect on cancer initiation"
Institution: Fred Hutchinson Cancer Research Center
Named Award: The Mark Foundation for Cancer Research Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Slobodan Beronja, PhD
Cancer Type: Skin
Research Area: Carcinogenesis