Dr. Burton studies how chemical modification of histone proteins leads to changes in the structure of chromatin, the physiologically relevant form of DNA, and how misregulation of this higher-order assembly can lead to aberrant gene transcription patterns and cancer. He will use chemical biology tools to carry out precise chemistry in live cells, and determine direct causality in the downstream effects on DNA accessibility and transcription.
Damon Runyon Researchers
Meet Our Scientists
Antony J. Burton, PhD
Project title: "Sculpting chromatin architecture in live cells using protein chemistry"
Institution: Princeton University
Award Program: Fellow
Sponsor(s) / Mentor(s): Tom W. Muir, PhD
Cancer Type: All Cancers
Research Area: Chromatin Biology
