Feng Zhang, PhD (Damon Runyon-Rachleff Innovator ‘12-‘14) of the Broad Institute and Massachusetts Institute of Technology, Cambridge, was named one of three recipients of the 2018 Vilcek Prize for Creative Promise in Biomedical Science. The awards from the Vilcek Foundation recognize young foreign-born biomedical scientists, 38 years old or younger, who demonstrate outstanding early achievement.  He is recognized for his groundbreaking work in the field of CRISPR genome editing.

Ron Levy, MD (Emeritus Board Member), and colleagues at Stanford University School of Medicine, Stanford, reported the success of an injectable "vaccine" delivered directly to tumors. The vaccine combines two key agents, a short piece of DNA called CpG oligonucleotide with an antibody that binds to OX40, thus activating immune T cells to fight cancer cells. In mice, they found that it could eliminate all traces of the injected tumors, including untreated metastases in the same animal.

Amanda Balboni Iniguez, PhD (Damon Runyon-Sohn Fellow ’15-’19) and colleagues at Dana-Farber Cancer Institute, Boston, reported that a class of cancer drugs called CDK inhibitors may be able to disarm a gene that causes Ewing sarcoma, the second most common form of bone tumor in young people. They showed in mouse models of Ewing sarcoma that CDK12 inhibitors could slow down tumor growth and extend life.

Mark W. Zimmerman, PhD (Damon Runyon-Sohn Fellow ’14-’18) and colleagues at the Dana-Farber Cancer Institute, Boston, have identified mechanisms that drive about 10 percent of high-risk neuroblastoma cases. Neuroblastoma is the most common solid tumor affecting infants and young children with few effective treatment options. The researchers found that a protein called c-MYC could cause neuroblastoma, when it is produced at abnormally high levels in tumor cells in a zebrafish model.

When young scientists earn a Damon Runyon award, they join one of science’s most prestigious and collaborative communities, a community dedicated to fostering the next generation of breakthrough cancer researchers.  Former Damon Runyon fellow in the 1980s, Jim Wells, PhD, Professor in the Department of Pharmaceutical Chemistry at UCSF and a member of our Board of Directors has mentored seven Damon Runyon Fellows, all of whom have gone on to highly successful careers in biomedical research.

We recently sat down with Jim to discuss how mentorship shaped his own career and why he continues to bring Damon Runyon fellows into his lab.

The National Academy of Sciences (NAS) will honor 19 individuals with awards in recognition of their extraordinary scientific achievements in a wide range of fields spanning the physical, biological, and medical sciences.  Congratulations to Damon Runyon alumnus and mentor Howard Y.

In Time Magazine's The Boss, successful women like Damon Runyon's Lorraine Egan share how they reached the top and the lessons they learned along the way.

At the end of last year, Norman E. Sharpless, M.D., was appointed Director of the National Cancer Institute (NCI).  In this critically important role, he oversees the federal government’s $6 billion annual investment in cancer research.  We know him well, as Dr. Sharpless has served on the selection committee for the Damon Runyon Clinical Investigator Award.  

The Damon Runyon-Jake Wetchler Award for Pediatric Innovation is given annually to a third-year Damon Runyon Fellow whose research has the greatest potential to impact the prevention, diagnosis or treatment of pediatric cancer. In its second year, Amanda Balboni Iniguez, PhD, received the award at the annual Fellows' Retreat.

Damon Runyon Broadway Tickets offers Broadway’s best seats and the opportunity to support cutting edge cancer research at the same time.

Some of our most loyal customers, like Rocco Staino, have been purchasing their Broadway tickets through us for years or even decades. Mr. Staino is the retired director of the Keefe Library of the North Salem School District in New York, and a contributing editor for School Library Journal and also writes for the Huffington Post.