Early Detection of Ovarian and Lung Cancers

For many years, scientists have unsuccessfully attempted to detect microscopic elements of tumors in blood for the purpose of diagnosing cancer in its early stages.  With the recent advancements in computing power and DNA sequencing, Dr. Tewari is able to pursue a new line of investigation focused on microRNAs – a course which could finally lead to a solution.

Dr. Tewari has discovered that certain microRNAs are only made by tumor cells and that these can be detected in blood samples.  His work could lead to the development of a highly sensitive blood test for cancers, particularly ovarian and lung, both of which are notoriously difficult to detect in their initial stages.

Dr. Tewari said, “We have come to a point where a substantially new approach for early detection has opened up, yet the work is so early that traditional sources of funding are not willing to invest in it. Thanks to the Foundation and the Rachleffs’ vision and support, the concept will be able to be developed with full vigor.”

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Project Title: "Cancer detection in "pre-diagnosis" blood samples via microparticle-associated small RNAs"

Institution: Fred Hutchinson Cancer Research Center

Sponsor(s) / Mentor(s): n/a

Cancer Type: All cancers

Research Area: Diagnostics